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Does creatine improve cognition?

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Creatine supplementation's impact on cognitive function has been extensively studied, with varying results. Here are some key findings: 1. **Improvement in Short-Term Memory and Intelligence/Reasoning**: Creatine supplementation may enhance short-term memory and intelligence/reasoning in healthy individuals. However, its effects on other cognitive domains such as long-term memory, spatial memory, and attention are less clear [(Avgerinos et al., 2018)](https://consensus.app/papers/effects-creatine-supplementation-function-individuals-avgerinos/18d9668a534e5ac19ee3584100be5300/?utm_source=chatgpt). 2. **No Significant Improvement in Young Adults**: In non-sleep deprived young adults, six weeks of creatine supplementation did not show improvement in cognitive processing or psychomotor performance [(Rawson et al., 2008)](https://consensus.app/papers/creatine-supplementation-improve-function-adults-rawson/abdae5a53e165b91aedc1b5fba636e27/?utm_source=chatgpt). 3. **Potential Benefit in Conditions with Brain Creatine Deficits**: Creatine supplementation might be beneficial for cognitive processing, especially in conditions characterized by brain creatine deficits, such as acute stressors or chronic pathologic conditions [(Roschel et al., 2021)](https://consensus.app/papers/creatine-supplementation-brain-health-roschel/50cee16b35b8502590e8c88c4b037053/?utm_source=chatgpt). 4. **Varied Response Based on Dietary Habits**: Vegetarians responded better than meat-eaters in memory tasks after creatine supplementation [(Avgerinos et al., 2018)](https://consensus.app/papers/effects-creatine-supplementation-function-individuals-avgerinos/18d9668a534e5ac19ee3584100be5300/?utm_source=chatgpt). 5. **No Improvement in Brain Creatine Content or Cognitive Performance in Youth**: A 7-day creatine supplementation protocol did not elicit improvements in brain creatine content or cognitive performance in healthy youth [(Merege-Filho et al., 2017)](https://consensus.app/papers/does-brain-creatine-content-rely-creatine-youth-meregefilho/b2bca4827453515c839953a203e9cff8/?utm_source=chatgpt). 6. **Positive Impact on Cognitive Function in Specific Populations**: Creatine supplementation showed positive effects on cognitive function in specific populations, like young women and fatigued healthcare professionals [(Skelton & Dellis-Leeper, 2012; Skelton & Giamo, 2013)](https://consensus.app/papers/effect-creatine-monohydrate-supplementation-function-skelton/f52201a1c35e506591ba20d6b02407b9/?utm_source=chatgpt). 7. **Potential Role in Neuroprotection and Cognitive Enhancement**: Creatine may have neuroprotective and cognitive-enhancing properties, especially under conditions of oxygen deprivation or in neurodegenerative diseases [(Turner et al., 2015)](https://consensus.app/papers/creatine-supplementation-enhances-corticomotor-turner/e15b561be048539fad622e763ff87110/?utm_source=chatgpt). In conclusion, while creatine supplementation may improve certain aspects of cognitive function, particularly in short-term memory and intelligence/reasoning, the overall effects are mixed and may vary based on age, health status, and dietary habits. Further research, especially in diverse populations and under various conditions, is warranted.