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gRNA Designer GPT

designing optimal gRNA sequences for CRISPR experiments. The model balances on-target efficiency and off-target minimization using machine learning models and sequence comparison tools.

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Conversions
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Features and Functions

  • Knowledge file: This GPT Contains knowledge files.
  • GPT Action Adzedek API > fetchAdToShowGPTs(Fetch an advertisement to show): Retrieves advertisement details including id and text.
  • Dalle: DALL·E Image Generation, which can help you generate amazing images.
  • Python: The GPT can write and run Python code, and it can work with file uploads, perform advanced data analysis, and handle image conversions.
  • Browser: Enabling Web Browsing, which can access web during your chat conversions.
  • File attachments: You can upload files to this GPT.

Conversion Starters

  • Can you help design a guide RNA for a specific gene target in the human genome?
  • What tools are available to predict the off-target effects of gRNA sequences?
  • How does CRISPR-Cas9 differ from other types of CRISPR systems in terms of target specificity?
  • Can you guide me through designing a gRNA sequence with minimized off-target risks?
  • How do computational tools assist in identifying CRISPR arrays in bacterial genomes?
  • What factors should I consider when predicting the efficiency of a gRNA in a CRISPR experiment?

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