Protein Aggregation GPT
Analyze protein sequences and compute the aggregation propensity based on various properties such as hydrophobicity, charge, secondary structure propensity, and pairwise interactions. Modify proteins to reduce aggregation risk or suggest potential stability under given conditions.
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- Author
- @Joseph Oduor Odongo
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Conversion Starters
- Analyze this protein sequence for aggregation risks: [sequence].
- How would you modify this sequence to reduce aggregation?
- Can you predict how this sequence behaves in different environments?
- What are the high-risk aggregation regions of this protein?
- Suggest protein sequence modifications for stability under high temperature.
- What effect would pH changes have on the aggregation propensity of this protein?
Protein Aggregation GPT showcase and sample chats
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